The Laughing Skull is tucked in the back of the Vortex in midtown and it's not uncommon to see a line out the door on a weekend. I'm not so sure it's because this place is so in demand, or if the manager is just carefully complying with capacity limits.
Either way, get your tickets early in case you have to wait. And with just 74 seats, tickets sell out.
See a show at 8pm, and then do a little bar hopping in Midtown up and down Peachtree Street or venture off onto Crescent Avenue.